Mouse Anti-Human TREM-1

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Cat-Nr.101-M687
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#9T3)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of Human TREM-1 recombinant protein.
Antigenrecombinant human TREM-1 EC domain
ApplicationWB, Stimulation
SynonymsTREM1; CD354; TREM-1
DescriptionThe TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. The receptors are members of the immunoglobulin superfamily, characterized structurally by a single V-set immunoglobulin (Ig) domain and a short cytoplasmic tail. TREMs associate with the DAP12 signal adapter, an immunoreceptor tyrosine-based activation motif- (ITAM)-containing protein that is phosphorylated and transduces signals when activated.
Uniprot IDQ9NP99
Protein RefSeqNP_061113.
mRNA RefSeqNM_018643

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