Mouse Anti-Human IGF-1 Receptor

Slide this table

Cat-Nr.101-M455
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#5J32)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IGF-I Receptor extracellular domain.
Antigenrecombinatn human IGF-I R EC domain
ApplicationWB, N
SynonymsIgf1r; hyft; CD221; IGF-1R; D930020L01; A330103N21Rik
DescriptionIGF-I receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha and two beta subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The alpha subunit of IGF-I receptor is extracellular while the beta subunit has an extracellular domain, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The IGF-I receptor is highly expressed in all cell types and tissues.
Uniprot IDP08069
Protein RefSeqNP_000866.1
mRNA RefSeqNM_000875.3

All prices plus VAT + possible delivery charges