Rat Anti-Mouse FGFR-3

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Size100 µg
Price350 €
CategoryMonoclonal Antibody
Clone Nr.(#7M13)
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
AntigenMouse recombinant protein FGF R3
SynonymsFibroblast growth factor receptor 3, FGFR-3, Heparin-binding growth factor receptor, CD333
DescriptionFibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N terminal signal peptide, three immunoglobulin (Ig)like domains, an acid box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine kinase domain.
Uniprot IDQ61851
Protein RefSeqNP_001156687.1
mRNA RefSeqNM_001359036.1

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