Mouse Anti-Human FGFR-2

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Cat-Nr.101-M416
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#6L19)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThe antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with the recombinant extracellular domain of human Fibroblast Growth Factor Receptor-2 (sFGFR-2). The IgG1 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography.
AntigenRecombinant human FGF-R2 EC domain
ApplicationWB, IHC (P), N
SynonymsFGFR2; BEK; JWS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
DescriptionFibroblast Growth Factor Receptor 2 (FGF R2) is one of four closely related transmembrane tyrosine kinases (FGF R1-4) that function as receptors for the fibroblast growth factor family. Multiple isoforms are generated by alternative mRNA splicing resulting in extracellular domains with three (α isoforms) or two (β isoforms) Ig-like domains. In addition, alternative exon usage in the Ig III (membrane proximal) domain results in IIIb or IIIc isoforms.
Uniprot IDP21802
Protein RefSeqNP_000132
mRNA RefSeqNM_000141

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