Mouse Anti-Human Trk-B

Slide this table

Cat-Nr.101-M689
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#7Y6)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human Trk-B recombinant protein.
Antigenhuman recombinant Trk-B
ApplicationWB, IHC (F)
SynonymsNTRK2; TRKB; trk-B; GP145-TrkB
DescriptionMembers of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth.
Uniprot IDQ16620
Protein RefSeqNP_006171
mRNA RefSeqNM_006180

All prices plus VAT + possible delivery charges