Mouse Anti-Human IL-2 receptor alpha

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Cat-Nr.101-M710
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#1X27)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-2 Ra extracellular domain.
Antigenrecombinant human IL-2 R alpha EC domain
ApplicationWB, IHC (P), N
SynonymsIL2RA; CD25; IL2R; TCGFR; IDDM10
DescriptionIL2-Ra is one of the three constituent subunits of the IL2 receptor. IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas. Interleukin-2R Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (22-213) corresponding to the mature IL2-R protein with an amino terminal hexahistidine tag. The IL-2R is purified by proprietary chromatographic techniques.
Uniprot IDP01589
Protein RefSeqNP_000408.1
mRNA RefSeqNM_000417.2

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