Rat Anti-Mouse IFN gamma

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Cat-Nr.103-M533
Size100 µg
Price350 €
CategoryMonoclonal Antibody
Clone Nr.(#7A13)
IsotypeIgG2
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationProduced from sera of rabbits pre-immunized with highly pure (>98%) recombinant murine IFN-gamma (murine Interferon-gamma). Anti-murine IFN-gamma specific antibody was purified by affinity chromatography employing immobilized murine IFN-gamma matrix.
Antigen Recombinant mouse IFN-gamma
ApplicationWB, FC
SynonymsIfng; Ifg; IFN-g
DescriptionIFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.
Uniprot IDP01580
Protein RefSeqNP_032363
mRNA RefSeqNM_008337

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