Mouse Anti-Human IL-7 receptor alpha

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Cat-Nr.101-M509
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#10V5)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-7Ra extracellular domain (also called CD127).
Antigenrecombinant human IL-7R alpha EC domain
ApplicationWB
SynonymsIL7R; ILRA; CD127; IL7RA; CDW127; IL-7R-alpha
DescriptionThe biological effects of IL-7 are mediated by the binding of IL-7 to the specific cell surface receptor complex. The functional high-affinity IL-7 receptor (IL-7 R) comprises the IL-7 R alpha chain in association with the common gamma chain (gamma c). Both IL-7 R alpha and gamma c are members of the hematopoietin receptor superfamily. Human and mouse IL-7 R alpha show 64% amino acid sequence identity. IL-7 R alpha transcripts were observed in murine spleen, thymus, fetal liver, developing T cells, B cells, mature T cells and bone marrow-derived macrophages.
Uniprot IDP16871
Protein RefSeqNP_002176.2
mRNA RefSeqNM_002185.2

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