Rat Anti-Mouse Fc gamma RIII

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Cat-Nr.103-M528
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#21Q2)
IsotypeIgG2
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
AntigenRecombinant mouse Fc gamma RIIb
ApplicationWB
SynonymsLow affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII (FcRIII), CD16
DescriptionReceptors for the Fc region of IgG (Fc γ Rs) are members of the Ig superfamily that function in the activation or inhibition of immune responses such as degranulation, phagocytosis, ADCC (antibody-dependent cellular toxicity), cytokine release, and B cell proliferation. The Fc γ Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc γ RI (also known as CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type.
Uniprot IDQ5D5J5
Protein RefSeqNP_001391947.1
mRNA RefSeq NM_001405018.1

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