Mouse Anti-Human Aggrecan

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Cat-Nr.101-M213
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#23A8)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human Aggrecan recombinant protein.
Antigenrecombinant human Aggrecan
ApplicationWB, IHC (P)
SynonymsACAN; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP
DescriptionAggrecan, together with type II collagen, makes up to 90% of the dry weight of healthy cartilage. It hydrates the collagen network and thus provides cartilage with its properties of compressibility and elasticity. The N-terminal region of human Aggrecan (residues 20-675) consists of two globular domains (G1 and G2), flanking an interglobular domain (IGD). The IGD contains the cleavage sites for matrix metalloproteinases and aggrecanases.
Uniprot IDE7ENV9
Protein RefSeqNP_001126.3
mRNA RefSeqNM_001135.3

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