Rat Anti-Mouse CD8a

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Cat-Nr.103-M106
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#MAB0708)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse Thymus/Spleen Tissues. IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography.
AntigenMouse Thymus and Spleen Tissues
ApplicationIHC, FC
SynonymsCd8a; Ly-2; Ly-B; Ly-35; Lyt-2; BB154331
DescriptionCD8 is a heterodimeric glycoprotein consisting of an alpha and beta chain. It is expressed on cytolytic T cells and functions in conjunction with the T cell receptor in the recognition of MHC/peptide complexes.
Uniprot IDP01731
Protein RefSeqNP_001074579.1
mRNA RefSeqNM_001081110.2

Reference

  1. Vaccine-induced Aβ-specific CD8+ T cells do not trigger autoimmune neuroinflammation in a murine model of Alzheimer's disease. Rosset M.B. et al., J Neuroinflammation. 2015 May 16;12:95.

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