Mouse Anti-Human NT-4

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Cat-Nr.101-M15
Size500 µg
Price250 €
CategoryMonoclonal Antibody
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized from PBS
BufferPBS
ReconstitutionReconstitute the antibody in sterile water to a concentration of 1.0mh/mL.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced in BALB/c x c57BL/6 F1 mice using recombinant human NT-4 as the immunizing antigen. IgG2a antibody was purified from ascites fluid on a Protein A affinity column.
AntigenRecombinant Human NT-4
ApplicationELISA
SynonymsNTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5
DescriptionNT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
Uniprot IDP34130
Protein RefSeqNP_006170.1
mRNA RefSeqNM_006179.4

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