Hamster Anti-Mouse Podoplanin
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|Reconstitution||Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.|
|Stability and Storage||The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.|
|Preparation||Monoclonal antibodies were produced by immunizing Syrian hamsters with a murine thymic stromal cell line. This antibody recognizes mouse Podoplanin. Hamster IgG antibody from hybridomas was purified from cell culture supernatant by Protein G chromatography.|
|Antigen||murine stromal cell line|
|Application||WB, IHC, IP|
|Synonyms||Pdpn; T1a; Gp38; OTS-8; T1alpha; RANDAM-2; T1-alpha|
|Description||Podoplanin, also known as T1 alpha (T1α), is a mucin type transmembrane glycoprotein with extensive O-glycosylation. It is specifically expressed by lymphatic endothelial cells but not blood vascular endothelial cells. In addition, non-endothelial cells in numerous normal tissues also express the protein. Within the region used as the immunogen, mouse Podoplanin shares 73.5% and 29% amino acid sequence homology with rat and human Podoplanin, respectively.|
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