Rat Anti-Mouse CD28

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Cat-Nr.103-M513
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#17E9)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a Golden Syrian Hamster immunized with recombinant mouse CD28 protein). IgG fraction of the culture supernatant was purified by Protein G affinity chromatography.
AntigenRecombinant mouse CD28
ApplicationWB
DescriptionCD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Mouse CD28 is expressed constitutively on virtually 100% of mouse Tcells and on developing thymocytes.
Uniprot IDP31041
Protein RefSeqNP_031668.3
mRNA RefSeqNM_007642.4

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