Mouse Anti-Human Coagulation Factor II

Slide this table

Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#10B23)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Coagulation factor II (also called thrombin).
AntigenHuman recombinant Coagulation factor II
SynonymsMCFD2; F5F8D; SDNSF; F5F8D2; LMAN1IP
DescriptionCoagulation Factor II/thrombin is an essential component of the coagulation cascade in which it converts fibrinogen to fibrin, activates coagulation factors V, VII, VIII, XIII and forms complexes with protein C and thrombomodulin. It also activates platelets and regulates the behavior of additional cells through protease-activated receptors (PARs). A plasma serine protease, thrombin is synthesized as a 622 amino acid precursor with a 24 amino acid signal peptide and a 19 residue pro peptide. The mature chain can be further processed into several forms including those designated as alpha-, beta- and gamma-thrombin.
Uniprot IDP00734
Protein RefSeqNP_000497.1
mRNA RefSeqNM_000506.3

All prices plus VAT + possible delivery charges