Mouse Anti-Human CD28

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Cat-Nr.101-M301
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#12B3)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD28 extracellular domain.
AntigenHuman recombinant CD28 EC domain
ApplicationWB, FC, Stimulation
SynonymsCD28; Tp44
DescriptionCD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Mouse CD28 is expressed constitutively on virtually 100% of mouse Tcells and on developing thymocytes.
Uniprot IDP10747
Protein RefSeqNP_001230007.1
mRNA RefSeqNM_001243078.1

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