Mouse Anti-Human LIF R alpha

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Cat-Nr.101-M554
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#9B23)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of LIFRa extracellular domain.
Antigenrecombinant human LIFR alpha EC doamin
ApplicationWB, FC
SynonymsLIFR; SWS; SJS2; STWS; CD118; LIF-R
DescriptionThe activities of the pleiotropic cytokine LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins: an alpha subunit (LIF R alpha, also known as LIF R beta and CD118) that binds LIF with low affinity and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex.
Uniprot IDP42702
Protein RefSeqNP_001121143.1
mRNA RefSeqNM_001127671.1

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