Mouse Anti-Human IL-1 R8

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#3R16)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL1 R8 extracellular domain.
Antigenrecombinant human IL1-R 8 EC domain
SynonymsIL1RAPL1; IL1R8; MRX10; MRX21; MRX34; OPHN4; IL1RAPL; TIGIRR-2; Interleukin 1 receptor 8
DescriptionThe Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. Interleukin 1 receptor accessory protein-like 1 (IL-1 RAPL1), also known as IL-1 R8, Oligophenin-4 (OPHN4) and three immunoglobulin domain containing IL-1 receptor-related 2 (TIGIRR-2), is a member of the IL-1 receptor superfamily.
Uniprot IDQ9NZN1
Protein RefSeqNP_055086.1
mRNA RefSeqNM_014271.3

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