Mouse Anti-Human Orexin B

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Cat-Nr.101-M596
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#5G21)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of Orexin-B.
Antigenhuman Orexin-B peptide (aa71-96, O43621)
ApplicationIHC (F)
SynonymsOrexin B
DescriptionOrexin B is a hypothalamic neuropeptide that regulates feeding behavior. This peptide significantly augments food intake in a dose-dependent manner when a bolus was administered intracerebroventricularly. After a 48 hour fast, hypothalamic prepro-orexin mRNA level is up-regulated 2.4. The discovery of Orexins and their receptors may provide a novel molecular basis for understanding the role of the lateral hypothalamic areas in the regulation of energy homeostasis.
Uniprot IDO43612
Protein RefSeqNP_001515.1
mRNA RefSeqNM_001524.1

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