Mouse Anti-Human IL-4R alpha

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#4Y44)
Species ReactivityHuman
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
AntigenHuman recombinant IL-4R alpha EC domain
ApplicationWB, IHC (P), N
SynonymsIl4ra; Il4r; CD124
DescriptionTwo types of IL-4 receptor complexes have been described. The typeI IL-4 receptor complex is composed of a high-affinity IL-4-binding subunit (referred to as IL-4 R or IL-4 R alpha) and the common gamma chain that does not bind IL-4 by itself. The type II IL-4 receptor complex is composed of IL-4 R and IL-13 R alpha 1. Besides IL-4 signals, the type II IL-4 receptor complex can also transduce IL-13 signals. In the type II complex, IL-4 R subunit binds only IL-4 and not IL-13. Similarly, the IL-13 R alpha 1 subunit binds only IL-13 and not IL-4.
Uniprot IDP24394
Protein RefSeqNP_000409.1
mRNA RefSeqNM_000418

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