Mouse Anti-Human G-CSF R

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Cat-Nr.101-M431
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#8F19)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of G-CSF-R extracellular domain (also called CD114).
Antigenrecombinant human G-CSF-R EC domain
ApplicationWB, FC
SynonymsCSF3R; CD114; GCSFR
DescriptionHuman G-CSF R is 836 amino acids (aa) in length, with a 23 aa signal sequence, a 604 aa extracellular region, a 26 aa transmembrane segment, and a 183 aa cytoplasmic domain. As a result of alternative splicing, at least four isoforms of G-CSF R exist that differ in their transmembrane C-terminal region. Human and mouse G-CSF R are 64% identical at the aa level. G-CSF R is expressed in mature neutrophils, neutrophilic precursors, myeloid leukemia cells, and placenta.
Uniprot IDQ99062
Protein RefSeqNP_000751.1
mRNA RefSeqNM_000760.3

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