Mouse Anti-Human CRIM1

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Cat-Nr.101-M340
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#16G1)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant CRIM1 extracellular domain.
AntigenHuman recombinant CRIM1 EC domain
ApplicationWB
SynonymsCRIM1; S52; CRIM-1
DescriptionCRIM1, also known as cysteine rich motor neuron 1, is a type I transmembrane glycoprotein containing an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 CRRs are similar to those in the BMP-binding antagonists such as Chordin. CRIM1 can interact with TGF-beta family ligands to modulate TGF-beta family ligand functions.
Uniprot IDQ9NZV1
Protein RefSeqNP_057525.1
mRNA RefSeqNM_016441.2

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