Mouse Anti-Human Complement Factor D

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Cat-Nr.101-M335
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#4M47)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Complement factor D (also called Adipsin).
Antigenhuman recombinant Complement factor D
ApplicationWB
SynonymsCFD; DF; ADN; PFD; ADIPSIN
DescriptionComplement Factor D, also known as adipsin, is a serine protease that catalyzes the initial proteolytic step in the alternative pathway of complement. It is an exceptionally specific protease and the only known protein substrate is factor B in complex with C3.3 Factor D protease activity is regulated by reversible conformational changes, which differs from the majority of serine proteases whose regulation involves either activation by processing of the zymogens or inactivation by binding of the inhibitors.
Uniprot IDP00746
Protein RefSeqNP_001919.2
mRNA RefSeqNM_001928.2

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