Mouse Anti-Human EDG-1

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Size100 µg
Price350 €
CategoryMonoclonal Antibody
Clone Nr.(#21L9)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with human recombinant Endothelial Differentiation Gene-1 (EDG-1) protein. IgG1 fraction of culture supernatant was purified by Protein G affinity chromatography.
Antigenrecombinant human EDG-1 protein
ApplicationWB, IHC (P), FC
SynonymsS1PR1; EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362
DescriptionS1P1, also known as EDG1, is a member of the endothelial differentiation gene family. It is a high affinity G proteincoupled receptor for the bioactive lipid, Sphingosine1phosphate. S1P1 signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis.
Uniprot IDP21453
Protein RefSeqNP_001391.2
mRNA RefSeqNM_001400.4

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