Hamster Anti-Mouse IL-10 receptor alpha

Slide this table

Cat-Nr.103-M242
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#9E12)
IsotypeIgG
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-10R extracellular domain. The IgG fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
AntigenMouse recombinant EC domain of IL-10R
ApplicationWB, IHC (P)
SynonymsIl10ra; Il10r; CDw210; CDw210a; mIL-10R; AW553859
DescriptionHuman and mouse IL-10 receptors are structurally related to the IFN-gamma receptor. These receptors are members of the class II subgroup of the cytokine receptor superfamily. The deduced amino acid sequence of human IL-10 R is approximately 60% identical to mouse IL-10 R. Although human IL-10 has cross-species activities and is active on mouse cells, mouse IL-10 is species-specific in its actions and does not bind to the human IL-10 receptor. The human IL-10 R gene has been mapped to chromosome 11q23.3. Recombinant IL-10 soluble receptor, consisting of the extracellular domain of IL-10 R, binds IL-10 with high affinity in solution and is a potent IL-10 antagonist.
Uniprot IDQ61727
Protein RefSeqNP_032374.1
mRNA RefSeqNM_008348.2

All prices plus VAT + possible delivery charges