Rat Anti-Mouse Marapsin

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Cat-Nr.103-M433
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#9D66)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of Marapsin (also called Pancreasin).
Antigenmouse recombinant protein of Marapsin
ApplicationWB
SynonymsPrss27; Mpn; CAPH2; marapsin
DescriptionMarapsin, Pancreasin, and channel-activating protease 2 (CAP2), encoded by the Prss27 gene, are different names given for the same serine protease that is expressed strongly in the pancreas. The mouse protein is synthesized with a signal peptide (amino acid residues 1-22), a pro peptide (residues 23-37)and amature chain (residues 38-290)corresponding to the serine protease domain. The fulllengthprotein was expressed and the secreted protein purified. The N-terminalsequencing results indicate that the purified protein is a disulfide bond-linked dimer formed between the pro peptide and the mature chain. The active enzyme has lowactivity against peptide substrates tested, but high activity against thioester substrates. The peptidase activity is inhibited by 20 mM benzamidine.
Uniprot IDQ8BJR6
Protein RefSeqNP_780649.1
mRNA RefSeqNM_175440.4

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