Mouse Anti-Human RANTES

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Cat-Nr.101-M16
Size500 µg
Price250 €
CategoryMonoclonal Antibody
IsotypeIgG2b
Species ReactivityHuman
Formulationlyophilized from PBS
BufferPBS
ReconstitutionReconstitute the antibody in sterile water to a concentration of 1.0mh/mL.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationMonoclonal antibody against human RANTES designated as VL-1 was purified from ascites fluid on a Protein A affinity column. The monoclonal antibody was derived form BALB/c mice and belongs to the IgG2b isotype.
AntigenRecombinant Human RANTES (CCL5)
ApplicationELISA, N, WB, IHC
SynonymsCCL5; SISd; SCYA5; RANTES; TCP228; D17S136E
DescriptionRANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Uniprot IDP13501
Protein RefSeqNP_002976.2
mRNA RefSeqNM_002985

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