Mouse Anti-Human DCIR

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Cat-Nr.101-M375
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#5P20)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant DCIR (also called CLEC4A or CLEC6) extracellular domain.
AntigenHuman recombinant DCIR EC domain
ApplicationWB, FC
SynonymsCLEC4A; DCIR; LLIR; DDB27; CLECSF6; HDCGC13P
DescriptionDCIR, also known as Lectin-like Immunoreceptor (LLIR), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosinebased inhibitory motif (ITIM) in its cytoplasmic domain. Besides DC, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.
Uniprot IDQ9UMR7
Protein RefSeqNP_057568.1
mRNA RefSeqNM_016184.3

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