Mouse Anti-Human Jagged-1

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Cat-Nr.101-M524
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#4A24)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Jagged-1.
Antigenrecombinant human Jagged-1
ApplicationWB, FC
SynonymsJAG1; AGS; AHD; AWS; HJ1; CD339; JAGL1
DescriptionJAG1 is a protein associated with Alagille syndrome. JAG1 has also been designated as CD339 (cluster of differentiation 339). The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Uniprot IDP78504
Protein RefSeqNP_000205.1
mRNA RefSeqNM_000214.2

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