Rat Anti-Mouse IL-21 receptor

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Cat-Nr.103-M250
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#7F27)
IsotypeIgG1
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-21R extracellular domain. The IgG1 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
AntigenMouse recombinant EC domain of IL-21 R
ApplicationWB
SynonymsIl21r; NILR
DescriptionIL-21 R, also called NILR (novel interleukin receptor) is a type I cytokine receptor with four conserved cysteine residues and an extracellular WSXWS motif. It is most closely related to IL-2 R beta and IL-9 R alpha. Mouse and human IL-21 R share 62% amino acid identity. IL-21 R is expressed on lymphoid tissues, peripheral B cells, and cell lines of T, B and natural killer cell lineage. IL-21 mediated signaling requires the common gamma chain in addition to IL-21 R.
Uniprot IDQ9JHX3
Protein RefSeqNP_068687.1
mRNA RefSeqNM_021887.2

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