Mouse TARC (CCL17)
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| Cat-Nr. | M10-058S |
| Size | 5 µg |
| Price | 75 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Length [aa] | 70 |
| Molecular Weight | 7.9 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract murine BW5147.3 thymic lymphoma cells. The ED50 for this effect is 10-40 ng/ml. |
| Species Reactivity | Mouse |
| Synonyms | Thymus and Activation Regulated Chemokine, CCL17, ABCD-2 |
| Description | TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Murine TARC (CCL17) is an 7.9 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines. |
| Protein Sequence | ARATNVGREC CLDYFKGAIP IRKLVSWYKT SVECSRDAIV FLTVQGKLIC ADPKDKHVKK AIRLVKNPRP |
| Uniprot ID | Q9WUZ6 |
| Protein RefSeq | NP_035462.2 |
| mRNA RefSeq | NM_011332.3 |
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