Mouse TARC (CCL17)

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Cat-Nr.M10-058S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation≥ 98% by SDS-PAGE gel and HPLC analyses
Length [aa]70
Molecular Weight7.9 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract murine BW5147.3 thymic lymphoma cells. The ED50 for this effect is 10-40 ng/ml.
Species ReactivityMouse
SynonymsThymus and Activation Regulated Chemokine, CCL17, ABCD-2
DescriptionTARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Murine TARC (CCL17) is an 7.9 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Protein SequenceARATNVGREC CLDYFKGAIP IRKLVSWYKT SVECSRDAIV FLTVQGKLIC ADPKDKHVKK AIRLVKNPRP
Uniprot IDQ9WUZ6
Protein RefSeqNP_035462.2
mRNA RefSeqNM_011332.3

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