Human GCP-2 (CXCL6)

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Cat-Nr.100-028
Size20 µg
Price199 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]72
Molecular Weight7.9 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.
Species ReactivityHamster, Monkey, Rat, Human, Bacteria
SynonymsCXCL6; GCP2; CKA-3; GCP-2; SCYB6
DescriptionGCP-2 is a connective tissue derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors.  GCP-2 selectively attracts neutrophils and has also been shown to exert anti-angiogenic activity.  Human GCP-2 is cross-react on murine cells.  Recombinant human GCP-2 is a 7.9 kDa protein containing 72 amino acid residues.
Protein SequenceVLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN
Uniprot IDP80163
Protein RefSeqNP_002984.2
mRNA RefSeqNM_002993.4

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