Human Relaxin-2

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Cat-Nr.100-113S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]53
Molecular Weight6.0 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityData not available.
Species ReactivityHuman
SynonymsH2 relaxin, RLN2
DescriptionRelaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.
Protein SequenceA-Chain: QLYSALANKC CHVGCTKRSL ARFC; B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
Uniprot IDP04090
Protein RefSeqNP_005050.2
mRNA RefSeqNM_005059.3

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