Human MCP-2 (CCL8)
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| Cat-Nr. | 100-066 |
| Size | 10 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 76 |
| Molecular Weight | 8.9 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/ml. |
| Species Reactivity | Hamster, Monkey, Mouse, Rat, Human |
| Synonyms | CCL8; HC14; MCP2; MCP-2; SCYA8; SCYA10 |
| Description | The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-2 is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. |
| Protein Sequence | QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP |
| Uniprot ID | P80075 |
| Protein RefSeq | NP_005614 |
| mRNA RefSeq | NM_005623 |
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