Human BRAK (CXCL14)

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Cat-Nr.100-139S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation98% by SDS-PAGE & HPLC analysis
Length [aa]77
Molecular Weight9.4 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by it's ability to chemoattract activated monocytes using a concentration range of 1.0-10.0 ng/ml.
Species ReactivityMouse, Human, Bacteria
SynonymsCXCL14; KEC; KS1; BMAC; BRAK; NJAC; MIP2G; MIP-2g; SCYB14
DescriptionBreast and Kidney-expressed chemokine (BRAK) is a CXC chemokine expressed in normal tissue in the absence of inflammatory stimuli, and infrequently expressed in cancer cell lines. BRAK is known to be a highly selective monocyte chemoattractant. However, main function and receptor selectivity is unknown at this time. BRAK contains the four highly conserved cysteine residues present in CXC chemokines. The sequence of the mature protein consists of 87 amino acid residues, and is approximately 30% homologous to the sequences of MIP-2 alpha and beta. Recombinant human BRAK is a 9.4 kDa protein containing 77 amino acid residues.
Protein SequenceSKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE
Uniprot IDO95715
Protein RefSeqNP_004878.2
mRNA RefSeqNM_004887.4

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