Human MIP-3 alpha (CCL20)
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| Cat-Nr. | 100-078 |
| Size | 20 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 70 |
| Molecular Weight | 8.0 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml. |
| Species Reactivity | Mouse, Rat, Human |
| Synonyms | CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20; MIP-3-alpha |
| Description | MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 alpha is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
| Protein Sequence | ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM |
| Uniprot ID | P78556 |
| Protein RefSeq | NP_004582.1 |
| mRNA RefSeq | NM_004591 |
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