Human MEC (CCL28)

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Cat-Nr.100-246
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]108
Molecular Weight12.3 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityDetermined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.
Species ReactivityHuman, Bacteria
ReconstitutionCentrifuge the vial prior to opening!
SynonymsCCL28; MEC; CCK1; SCYA28
DescriptionMEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary glad, mammary gland and colon. MEC signals through the CCR10 receptor and chemoattracts resting CD4, CD8 T-cells and eosinophils. MEC contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant human MEC is a 12.3 kDa protein containing 108 amino acid residues.
Protein SequenceSEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY
Uniprot IDQ9NRJ3
Protein RefSeqNP_683513.1
mRNA RefSeqNM_148672

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