Mouse MIP-3 beta (CCL19)

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Cat-Nr.M10-079
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]83
Molecular Weight9.2 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human mature dendritic cells using a concentration range of 10.0-100.0 ng/ml.
Species ReactivityHuman, Mouse, Monkey, Leech, Rat
SynonymsCcl19; ELC; CKb11; MIP3B; Scya19; exodus-3
DescriptionMIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Mouse urine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Protein SequenceGANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
Uniprot IDO70460
Protein RefSeqNP_036018.1
mRNA RefSeqNM_011888

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