Ovine Prolactin antagonist (G129R)

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Size50 µg
Price390 €
SourceE. coli
Purity Confirmation> 99% by SDS-PAGE & HPLC analyses
Length [aa]199
Molecular Weight23.0 kDa
N Terminal SequenceATPVCP
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityRecombinant oPRL G129R is devoid of agonistic activity and capable of inhibiting biological activity of oPRL or other lactogenic hormones as evidenced by proliferation assay of Nb2 or other cells. The truncated form is more potent inhibitor.
Species ReactivityOvine
ReconstitutionIt is recommended to reconstitute the lyophilized oPRL G129R in sterile water or 0.4% NaHCO3 adjusted tp pH 8-9, not less than 100µg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.
SynonymsMammotropin, Luterotropic hormone, Lutetropin
DescriptionRecombinant ovine prolactin, G129R mutein is one polypeptide chain containing 199 amino and an additional Ala at N-terminus acids and having a molecular mass of ~ 23 kDa, was purified by proprietary chromatographic techniques (no published information). It is available in two forms: as full size protein and it its DEL 9 aa truncated form from its N-terminus which has higher inhibitory activity.
Uniprot IDP01240
Protein RefSeqNP_001009306.1
mRNA RefSeqNM_001009306.1

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