Mouse Exodus-2 (CCL21)

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Cat-Nr.M10-005S
Size5 µg
Price95 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]110
Molecular Weight12.0 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract total murine T cell population using a concentration range of 10.0-100.0 ng/ml.
Species ReactivityHuman, Mouse, Monkey, Leech, Rat
SynonymsCcl21a; ALP; SLC; plt; CKb9; Tca4; 6Ckine; Scya21; 6CKBAC2; SCYA21a; Scya21b; AW987545
DescriptionExodus-2 is a CC chemokine that can signal through the CCR7 receptor. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant murine Exodus-2 is a 12.0 kDa protein containing 110 amino acid residues.
Protein SequenceSDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
Uniprot IDP84444
Protein RefSeqNP_035254
mRNA RefSeqNM_011124

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