Human MIP-3 beta (CCL19)

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Cat-Nr.100-079S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]77
Molecular Weight8.8 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological ActivityDetermined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.
Species ReactivityMonkey, Mouse, Human, Leech, Bacteria
ReconstitutionCentrifuge the vial prior to opening!
SynonymsCCL19; ELC; CKb11; MIP3B; MIP-3b; SCYA19
DescriptionMIP-3β is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Protein SequenceGTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
Uniprot IDQ99731
Protein RefSeqNP_006265
mRNA RefSeqNM_006274

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