Mouse BRAK (CXCL14)

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Cat-Nr.M10-139
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation≥ 98% by SDS-PAGE gel and HPLC analyses
Length [aa]77
Molecular Weight9.4 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human THP-1 monocytes supplemented with Anti-CXCL14.
Species ReactivityMouse, Human
SynonymsBreast and Kidney-expressed chemokine, bolekine, NJAC
DescriptionBreast and Kidney‐expressed chemokine (BRAK) is a CXC chemokine expressed in normal tissue in the absence of inflammatory stimuli, and infrequently expressed in cancer cell lines. BRAK is known to be a highly selective monocyte chemoattractant. However, main function and receptor selectivity is unknown at this time. BRAK contains the four highly conserved cysteine residues present in CXC chemokines. The sequence of the mature protein consists of 87 amino acid residues, and is approximately 30% homologous to the sequences of MIP‐2 α and β. Recombinant Murine BRAK (CXCL14) is a 9.4 kDa protein containing 77 amino acid residues.
Protein SequenceSKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIVTTKS MSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE
Uniprot IDQ9WUQ5
Protein RefSeqNP_062514.2
mRNA RefSeqNM_019568.2

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