Mouse MCP-2 (CCL8)
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| Cat-Nr. | M10-075 |
| Size | 20 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 74 |
| Molecular Weight | 8.5 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/ml. |
| Species Reactivity | Human, Mouse, Bacteria |
| Synonyms | Ccl8; HC14; Mcp2; MCP-2; Scya8; AB023418; 1810063B20Rik |
| Description | The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-2 is an 8.5 kDa protein containing 74 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. |
| Protein Sequence | GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP |
| Uniprot ID | Q9Z121 |
| Protein RefSeq | NP_067418.1 |
| mRNA RefSeq | NM_021443 |
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