Human SCGF-alpha

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Cat-Nr.100-098
Size10 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]305
Molecular Weight33.9 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its inhibitory effect on the proliferation of TF-1 cells previously grown in media containing GM-CSF. The ED50 for this effect was observed at 2.5 ng/ml.
Species ReactivityHuman
SynonymsCLEC11A; P47; SCGF; LSLCL; CLECSF3
DescriptionStem Cell Growth Factor-alpha (SCGF-alpha) is a newly discovered hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. Human SCGF-alpha is a non-glycosilated species-specific cytokine that can support growth of primitive hematopoietic cells, and in combination of EPO or GM-CSF, it promotes proliferation of erythroid and myeloid progenitors, respectively. Recombinant human SCGF-alpha is a 33.9 kDa polypeptide containing 305 amino acid residues.
Protein SequenceGHGARGAERE WEGGWGGAQE EEREREALML KHLQEALGLP AGRGDENPAG TVEGKEDWEM EEDQGEEEEE EATPTPSSGP SPSPTPEDIV TYILGRLAGL DAGLHQLHVR LHALDTRVVE LTQGLRQLRN AAGDTRDAVQ ALQEAQGRAE REHGRLEGCL KGLRLGHKCF LLSRDFEAQA AAQARCTARG GSLAQPADRQ QMEALTRYLR AALAPYNWPV WLGVHDRRAE GL
Uniprot IDQ9Y240
Protein RefSeqNP_002966.1
mRNA RefSeqNM_002975.2

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