Human PF-4 (CXCL4)

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Cat-Nr.100-093
Size20 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]70
Molecular Weight7.8 kDa
Endotoxin Levels< 0.1 ng /mg of protein (<1EU/mg).
Biological Activity Determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml.
Species ReactivityMouse, Trout, Human, Bacteria
ReconstitutionCentrifuge the vial prior to opening!
SynonymsPF4; PF-4; CXCL4; SCYB4
DescriptionPF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.
Protein SequenceEAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES
Uniprot IDP02776
Protein RefSeqNP_002610.1
mRNA RefSeqNM_002619.2

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