Human PF-4 (CXCL4)
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| Cat-Nr. | 100-093 |
| Size | 20 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 70 |
| Molecular Weight | 7.8 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml. |
| Species Reactivity | Mouse, Trout, Human, Bacteria |
| Synonyms | PF4; PF-4; CXCL4; SCYB4 |
| Description | PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. |
| Protein Sequence | EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES |
| Uniprot ID | P02776 |
| Protein RefSeq | NP_002610.1 |
| mRNA RefSeq | NM_002619.2 |
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