Mouse IL-17D

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Cat-Nr.M10-234S
Size5 µg
Price85 €
SourceE.coli
Formulationlyophilized
Purity Confirmation≥ 95% by SDS-PAGE gel and HPLC analyses.
Length [aa]183
Molecular Weight20.2 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to bind murine IL-17RB Fc Chimera in a functional ELISA.
Species ReactivityMouse
SynonymsInterleukin-17D
DescriptionIL‐17D is a disulfide‐linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL‐17 family of structurally‐related cytokines that share a highly conserved C‐terminal region, but differ from one another in their N‐terminal regions and in their distinct biological roles. The six known members of this family, IL‐17A through IL‐17F, are secreted as homodimers. IL‐17D has the ability to stimulate the production of IL‐6, IL‐8 and GM‐CSF, and inhibits hemopoiesis of myeloid progenitor cells in colony‐forming assays.Recombinant Murine IL-17D is a 40.6 kDa, disulfide-linked homodimer of two 183 amino acid, polypeptide chains.
Protein SequenceAGALRTGRRP ARPRDCADRP EELLEQLYGR LAAGVLSAFH HTLQLGPREQ ARNASCPAGG RAADRRFRPP TNLRSVSPWA YRISYDPARF PRYLPEAYCL CRGCLTGLYG EEDFRFRSTP VFSPAVVLRR TAACAGGRSV YAEHYITIPV GCTCVPEPDK SADSANSSMD KLLLGPADRP AGR
Uniprot IDReviewed Data Unavailable

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