Mouse MIP-2 (CXCL2, Gro-beta)

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Cat-Nr.M10-037S
Size5 µg
Price75 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]73
Molecular Weight7.8 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml.
Species ReactivityHuman, Mouse
SynonymsCxcl2; GROb; Gro2; Mip2; Scyb; MIP-2; Scyb2; MIP-2a; Mgsa-b; CINC-2a
DescriptionAll three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant mouse MIP-2 is a 7.8 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Protein SequenceAVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN
Uniprot IDP10889
Protein RefSeqNP_033166.1
mRNA RefSeqNM_009140.2

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