Bovine SRY

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Cat-Nr.B30-001
Size10 µg
Price250 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 90% by SDS-PAGE & visualized by silver stain
Length [aa]231
Molecular Weight26.8 kDa
N Terminal SequenceMFRVLN
Biological ActivityData not available.
Species ReactivityBovine
Bufferwater
ReconstitutionCentrifuge vial prior to opening. Bovine SRY should be reconstituted in PBS to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20 °C.
Stability and StorageThe lyophilized powder although stable at room temperature for 3 weeks, is best stored desiccated at -20 °C. Reconstituted bo SRY should be stored in working aliquots at -20 °C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA).
SynonymsSex-determining region Y protein; Testis-determining factor
DescriptionThe „Sex determining region of Y-Gen” (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex
Protein SequenceMFRVLNDDVYSPAVVQQQTTLAFRKDSSLCTDSHSANDQCERGEHVRESSQDHVKRPMNAFIVWSRERRRKVALENPKMKNSDISKQLGYEWKRLTDAEKRPFFEEAQRLLAIHRDKYPGYKYRPRRRAKRPQKSLPADSSILCNPMHVETLHPFTYRDGCAKTTYSQMESQLSRSQSVIITNSLLQKEHHSSWTSLGHNKVTLATRISADFPCNKSLEPGLSCAYFQYLE
Uniprot IDQ03255
Protein RefSeqNP_001014407.1
mRNA RefSeqNM_001014385.1

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