Slide this table
|> 90% by SDS-PAGE
|N Terminal Sequence
|Data not available.
|Centrifuge vial prior to opening. Bovine SRY should be reconstituted in PBS to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffered solutions.
|Stability and Storage
|The lyophilized powder although stable at room temperature for 3 weeks, is best stored desiccated at -20°C. Reconstituted bo SRY should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
|Sex-determining region Y protein; Testis-determining factor
|The „Sex determining region of Y-Gen” (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex
All prices plus VAT + possible delivery charges