Rat SDF-1 alpha (CXCL12)

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Cat-Nr.R20-052
Size10 µg
Price170 €
SourceE. coli
Formulationlyophilized
Purity Confirmation> 98% by SDS-PAGE & HPLC analyses
Length [aa]68
Molecular Weight7.9 kDa
Endotoxin Levels< 0.1 ng/µg of protein (<1EU/µg)
Biological ActivityDetermined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/ml.
Species ReactivityHuman
SynonymsCxcl12; Sdf1
DescriptionStromal cell-derived factor (SDF)-1 alpha and SDF-1 beta are the first cytokines initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. They are encoded by a single gene, PBSF, and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1 beta and absent from SDF-1 alpha. SDF-1/PBSF is highly conserved between species. Human mature SDF-1 shares approximately 99% amino acid sequence identity with the mouse protein.
Protein SequenceKPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK
Uniprot IDQ9QZD1
Protein RefSeqNP_071513.1
mRNA RefSeqNM_022177.3

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