Human MCP-4 (CCL13)
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| Cat-Nr. | 100-068 |
| Size | 20 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 75 |
| Molecular Weight | 8.6 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human monocytes using a concentration of 10.0-100.0 ng/ml. |
| Species Reactivity | Monkey, Mouse, Human, Leech |
| Synonyms | CCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13 |
| Description | The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-2 is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. |
| Protein Sequence | QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT |
| Uniprot ID | Q99616 |
| Protein RefSeq | NP_005399 |
| mRNA RefSeq | NM_005408 |
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